Pharmacokinetic Facts behind Cialis
Cialis is one of the bestselling drugs to treat impotence and erectile dysfunction in America (and throughout the world), second to the most well-known drug in the world - Viagra. Its popularity has been steadily increasing in the last few years, as its safety profile and use testimonials have backed the product efficiency up.
But how does the active ingredient in Cialis work on a molecular level? What are the pharmacokinetic facts behind Cialis, and what is the mechanism of action?
Active Ingredient in Cialis
The active ingredient in Cialis is "tadalafil". This is a drug which is in the same family as other similar active ingredients such as "vardenafil" and "sidenafil" - and therefore has a relatively similar mechanism of action.
Whilst we certainly aren't going to go through all of the pharmacokinetic facts in this article, we will point out a few key features of the drug, so that you know how this active ingredient can be differentiated from others of the same family.
Half Life of Tadalafil
The half life of a drug refers to the amount of time that it takes for the drug to be broken down by the body. The half life measures the amount of time required for a 100% dose to be reduced to 50% naturally.
Here are the facts for Cialis in regards to its half life:
- Half life of 17.5 hours.
- Excreted via faeces and urine.
This half life makes the effective duration of treatment of Cialis a lot longer than other drugs in the impotence family. In many cases, consumers have up to 48 hours for the effects of the drug to continue to be felt.
Mechanism of Action of Cialis
Essentially, Cialis works by inhibiting the production of something called a PDE5 transmitter, which is often responsible for the lack of an erection, even when a male is sexually stimulated.
By blocking this transmitter, the brain is able to send its instructions, uninterrupted, to the tissue in the penis, and therefore improve the ability of that particular individual to get an erection.
Thus, the only drawback of a product such as Cialis is that it does not treat the underlying cause of the issue. It simply treats the symptoms - and in saying this, for many people, that is absolutely satisfactory and ultimately all they want out of such a product.